Albena T Dinkova-Kostova Selected Research

Fibrosis (Cirrhosis)

3/2018	Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2).
9/2014	Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not with insulin resistance.

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Albena T Dinkova-Kostova Research Topics

Disease

33	Neoplasms (Cancer) 01/2022 - 02/2002
25	Inflammation (Inflammations) 01/2022 - 08/2006
19	Carcinogenesis 12/2020 - 01/2003
8	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 03/2005
7	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 09/2008
5	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2019 - 10/2011
4	Chronic Disease (Chronic Diseases) 01/2022 - 08/2008
4	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2013
4	Skin Neoplasms (Skin Cancer) 06/2015 - 04/2007
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 11/2012
3	Parkinson Disease (Parkinson's Disease) 01/2021 - 11/2009
3	Erythema 04/2016 - 10/2007
2	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2020
2	Melanoma (Melanoma, Malignant) 01/2022 - 10/2008
2	Non-alcoholic Fatty Liver Disease 01/2022 - 09/2014
2	Neuroinflammatory Diseases 01/2021 - 11/2009
2	Multiple Sclerosis 10/2020 - 11/2009
2	Insulin Resistance 03/2018 - 09/2014
2	Fibrosis (Cirrhosis) 03/2018 - 09/2014
2	Fatty Liver 03/2018 - 09/2014
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 05/2016 - 11/2009
2	Friedreich Ataxia (Friedreich's Ataxia) 05/2016 - 11/2009
2	Alzheimer Disease (Alzheimer's Disease) 05/2016 - 11/2009
2	Huntington Disease (Huntington's Disease) 01/2016 - 11/2009
2	Leukemia 08/2008 - 01/2007
1	Mouth Neoplasms (Oral Cancer) 01/2022
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Systemic Scleroderma (Systemic Sclerosis) 10/2021
1	Adenoma (Adenomas) 01/2021
1	Triple Negative Breast Neoplasms 01/2021
1	Autism Spectrum Disorder 01/2020
1	Leukopenia 01/2020
1	Obesity 01/2020
1	Neurodevelopmental Disorders 01/2020
1	Cytokine Release Syndrome 01/2020

Drug/Important Bio-Agent (IBA)

18	EnzymesIBA 12/2020 - 06/2004
13	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2004
11	sulforaphaneIBA 01/2020 - 08/2006
8	Transcription Factors (Transcription Factor)IBA 01/2022 - 10/2009
8	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2020 - 02/2004
7	CarcinogensIBA 12/2020 - 04/2007
6	quinone (benzoquinone)IBA 01/2021 - 03/2005
6	Oxidoreductases (Dehydrogenase)IBA 01/2021 - 03/2005
6	NAD (NADH)IBA 01/2021 - 06/2004
5	Pharmaceutical PreparationsIBA 12/2020 - 10/2011
5	AntioxidantsIBA 10/2020 - 11/2012
4	TBE 31IBA 03/2018 - 08/2008
4	IsothiocyanatesIBA 01/2013 - 02/2002
3	bardoxoloneIBA 01/2022 - 04/2011
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 10/2007
3	XenobioticsIBA 10/2018 - 06/2004
3	Glutathione (Reduced Glutathione)IBA 11/2015 - 01/2007
3	TriterpenesIBA 06/2015 - 07/2007
3	Azathioprine (Imuran)FDA LinkGeneric 12/2012 - 10/2011
3	isothiocyanic acidIBA 05/2010 - 04/2007
3	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2010 - 07/2007
2	itaconic acidIBA 10/2021 - 01/2018
2	Phosphotransferases (Kinase)IBA 01/2021 - 01/2020
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 12/2020 - 01/2013
2	Sulfhydryl Compounds (Thiols)IBA 12/2020 - 03/2005
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 12/2020 - 01/2019
2	Kelch-Like ECH-Associated Protein 1IBA 12/2020 - 01/2019
2	NADP (NADPH)IBA 10/2020 - 11/2015
2	CytokinesIBA 01/2020 - 11/2012
2	Reactive Nitrogen SpeciesIBA 01/2020 - 11/2009
2	Cysteine (L-Cysteine)FDA Link 01/2020 - 09/2015
2	NF-E2 Transcription FactorIBA 01/2019 - 09/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 03/2018 - 02/2014
2	LipidsIBA 03/2018 - 10/2007
2	Messenger RNA (mRNA)IBA 11/2012 - 01/2010
2	GlucosinolatesIBA 06/2012 - 07/2007
2	SirtuinsIBA 05/2012 - 12/2010
2	Oxygen (Dioxygen)IBA 06/2011 - 01/2003
2	glucoraphaninIBA 04/2010 - 07/2007
2	Oxidants (Oxidizing Agents)IBA 10/2008 - 10/2007
2	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)IBA 01/2007 - 06/2004
1	Heme (Haem)IBA 01/2022
1	Basic-Leucine Zipper Transcription FactorsIBA 01/2022
1	4-octyl itaconateIBA 10/2021
1	CarbonIBA 01/2021
1	BenzenesulfonamidesIBA 01/2021
1	Tyrosine (L-Tyrosine)FDA Link 01/2021
1	acetamideIBA 01/2021
1	Molecular Chaperones (Chaperone, Molecular)IBA 12/2020
1	Cullin Proteins (Cullins)IBA 12/2020
1	RibonucleotidesIBA 12/2020
1	Serine (L-Serine)FDA Link 12/2020
1	diazonaphthalenedisulfonic acid (NDS)IBA 10/2020
1	Folic Acid (Vitamin M)FDA LinkGeneric 10/2020
1	Glutamine (L-Glutamine)FDA Link 10/2020
1	SulfurIBA 10/2020
1	1- cyclopropyl- 3- (3- (5- morpholin- 4- ylmethyl- 1H- benzoimidazol- 2- yl)- 1H- pyrazol- 4- yl)ureaIBA 01/2020
1	AdipokinesIBA 01/2020
1	Nonesterified Fatty Acids (NEFA)IBA 01/2020
1	Aurora KinasesIBA 01/2020
1	Histones (Histone)IBA 01/2019

Therapy/Procedure

5	Chemoprevention 12/2020 - 08/2008
4	Therapeutics 01/2021 - 10/2011
3	Drug Therapy (Chemotherapy) 12/2020 - 08/2008
1	Radiotherapy 12/2020